Stroke | Correct Body Maintenance

Home » Articles » Stroke










High blood pressure has been identified as the most important risk factor for stroke and    elevated homocysteine levels are associated with hypertension(high blood pressure) and play a significant role in the creation.  While the most common genetic cause of severe       hyperhomocysteinaemia is believed to be the

deficiency of cystathionine-beta-synthase, which has been shown to result in a 40-fold increase in fasting homocysteine.    Other causes include the deficiency or impaired activity of methionine synthase due to genetic disorders of vitamin B12 metabolism. Outside of these genetic mutations  folate and vitamins B6 and B12 are   essential cofactors in the methylation cycle and                 homocysteine-methionine metabolism, and low  bioavailability and function of these nutrients due to the polymorphisms impair the remethylation of homocysteine to methionine, lending to a vicious cycle of compounding Homocysteine levels.     Certain nutritional and lifestyle components also play a role in the pathophysiology of                   hyperhomocysteinaemia. Deficiencies of folate, vitamins B6 and B12 due to poor nutrient intake, malabsorption, leaky gut, medications or the presence of certain  diseases may lead to abnormal homocysteine concentrations. Vegetarians may be at a higher risk of  hyperhomocysteinaemia due to insufficient vitamin B12       intake. While insufficient physical activity and excessive alcohol consumption have also been shown to  contribute to hyperhomocysteinaemia. Other factors can also raise homocysteine levels, including eating a poor diet, leaky gut           syndrome/poor absorption,  malnutrition, gastrointestinal illness, high amounts of stress, alcohol and drug use, and toxin exposure.  Natural treatments include taking specialized forms of B9; B6 and B12; exercising; lowering  intake of               inflammatory foods, and managing stress.